C₂₃H₂₆FN₃O₉

Base Information

• Chemical Name: C₂₃H₂₆FN₃O₉
• CAS No.: 1355034-83-1
• Molecular Formula: C₂₃H₂₆FN₃O₉
• Molecular Weight: 507.473
• Mol file: 1355034-83-1.mol

Synonyms:C₂₃H₂₆FN₃O₉

Chemical Property of C₂₃H₂₆FN₃O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₆FN₃O₉

There total 6 articles about C₂₃H₂₆FN₃O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one (13096-62-3) → C23H26FN3O9 (1355034-83-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1.33 h / -78 - 0 °C

1.2: 3.5 h / -78 °C

2.1: triethylsilane; boron trifluoride diethyl etherate / methanol; dichloromethane; acetonitrile / 4 h / -15 °C / Inert atmosphere

3.1: sodium hydroxide / methanol; dichloromethane / 2 h / 20 °C

4.1: boron trifluoride diethyl etherate / 0 - 20 °C

5.1: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water / 20 °C

With triethylsilane; n-butyllithium; boron trifluoride diethyl etherate; copper(II) sulfate; sodium L-ascorbate; sodium hydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetonitrile;

DOI:10.1016/j.bmcl.2011.10.062

Reference yield:

trimethyl(((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)ethynyl)silane (141196-28-3,141100-79-0) → C23H26FN3O9 (1355034-83-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / methanol; dichloromethane / 2 h / 20 °C

2: boron trifluoride diethyl etherate / 0 - 20 °C

3: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water / 20 °C

With boron trifluoride diethyl etherate; copper(II) sulfate; sodium L-ascorbate; sodium hydroxide; In methanol; dichloromethane; water;

DOI:10.1016/j.bmcl.2011.10.062

Reference yield:

2,3,4,6-tetra-O-benzyl-D-glucopyranoside (59531-24-7) → C23H26FN3O9 (1355034-83-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: acetic anhydride; dimethyl sulfoxide / 20 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 1.33 h / -78 - 0 °C

2.2: 3.5 h / -78 °C

3.1: triethylsilane; boron trifluoride diethyl etherate / methanol; dichloromethane; acetonitrile / 4 h / -15 °C / Inert atmosphere

4.1: sodium hydroxide / methanol; dichloromethane / 2 h / 20 °C

5.1: boron trifluoride diethyl etherate / 0 - 20 °C

6.1: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water / 20 °C

With triethylsilane; n-butyllithium; boron trifluoride diethyl etherate; acetic anhydride; copper(II) sulfate; dimethyl sulfoxide; sodium L-ascorbate; sodium hydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetonitrile;

DOI:10.1016/j.bmcl.2011.10.062

upstream raw materials:

(3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one

2,3,4,6-tetra-O-benzyl-D-glucopyranoside

trimethyl(((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)ethynyl)silane

4-Fluorobenzyl bromide

Downstream raw materials:

C₁₅H₁₈FN₃O₅

Refernces