4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin

Base Information

• Chemical Name: 4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin
• CAS No.: 83559-93-7
• Molecular Formula: C₁₄H₁₄F₆N₂
• Molecular Weight: 324.269
• Mol file: 83559-93-7.mol

Synonyms:4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin

Chemical Property of 4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin

There total 2 articles about 4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5,6-Dihydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-4H-1,2-diazepin (62284-33-7) → 4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin (83559-93-7)

Guidance literature:

palladium on activated charcoal; In methanol; acetic acid; for 5h; Ambient temperature;

Reference yield:

6,6-Dimethyl-2-phenyl-4,4,8,8-tetrakis(trifluormethyl)-1,5-diazabicyclo<3.3.0>oct-2-en (62118-80-3) → 4,5,6,7-Tetrahydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-1H-1,2-diazeptin (83559-93-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / 0.5 h / 200 °C

2: 86 percent / Pd(C) / acetic acid; methanol / 5 h / Ambient temperature

palladium on activated charcoal; In methanol; acetic acid;

upstream raw materials:

5,6-Dihydro-3-methyl-7-phenyl-5,5-bis(trifluormethyl)-4H-1,2-diazepin

6,6-Dimethyl-2-phenyl-4,4,8,8-tetrakis(trifluormethyl)-1,5-diazabicyclo<3.3.0>oct-2-en