C₃₄H₃₄BrIO₇

Base Information

• Chemical Name: C₃₄H₃₄BrIO₇
• CAS No.: 1193357-62-8
• Molecular Formula: C₃₄H₃₄BrIO₇
• Molecular Weight: 761.448
• Mol file: 1193357-62-8.mol

Synonyms:C₃₄H₃₄BrIO₇

Chemical Property of C₃₄H₃₄BrIO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₃₄BrIO₇

There total 13 articles about C₃₄H₃₄BrIO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C34H33IO7 (1193357-61-7) → C34H34BrIO7 (1193357-62-8)

Guidance literature:

With dilithium tetrabromonickelate(II); In tetrahydrofuran; toluene; at 0 ℃; for 18.5h; Inert atmosphere;

DOI:10.1246/cl.2009.934

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C34H34BrIO7 (1193357-62-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: tributylphosphine; diamide / toluene / 2.5 h / 0 - 20 °C / Inert atmosphere

4.1: dilithium tetrabromonickelate(II) / tetrahydrofuran; toluene / 18.5 h / 0 °C / Inert atmosphere

With dmap; tributylphosphine; dilithium tetrabromonickelate(II); diamide; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane; toluene; 3.1: |Mitsunobu Displacement;

DOI:10.1246/cl.2009.934

Reference yield:

4-benzyloxycinnamyl alcohol (87030-12-4) → C34H34BrIO7 (1193357-62-8)

Guidance literature:

Multi-step reaction with 9 steps

1.1: methanesulfonamide; AD-mix β / water; tert-butyl alcohol / 3.8 h / 0 °C / Inert atmosphere

2.1: pyridine / dichloromethane / 29 h / 0 - 20 °C / Inert atmosphere

3.1: potassium carbonate / methanol / 3 h / 0 °C / Inert atmosphere

4.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 - 20 °C / Inert atmosphere

5.1: 10 wt% Pd(OH)2 on carbon; hydrogen / ethyl acetate / 6.5 h / 20 °C

6.1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

7.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

7.2: Inert atmosphere

8.1: tributylphosphine; diamide / toluene / 2.5 h / 0 - 20 °C / Inert atmosphere

9.1: dilithium tetrabromonickelate(II) / tetrahydrofuran; toluene / 18.5 h / 0 °C / Inert atmosphere

With pyridine; 1H-imidazole; dmap; tributylphosphine; methanesulfonamide; dilithium tetrabromonickelate(II); diamide; AD-mix β; 10 wt% Pd(OH)2 on carbon; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene; tert-butyl alcohol; 8.1: |Mitsunobu Displacement;

DOI:10.1246/cl.2009.934

upstream raw materials:

C₁₄H₁₈O₅

C₃₄H₃₃IO₇

4-hydroxy-benzaldehyde

p-benzyloxybenzaldehyde

Downstream raw materials:

C₄₀H₄₈O₇Si

C₃₅H₄₀O₅Si

C₂₉H₂₆O₅

(2S,3R)-2,3-trans-4',5,7-trihydroxyflavan-3-ol