Technology Process of C39H49N8O4(1+)
There total 4 articles about C39H49N8O4(1+) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
rhodamine B 4-(3-carboxypropionyl)piperazine amide;
With
benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
for 0.166667h;
Inert atmosphere;
3-azidopropylamine;
In
N,N-dimethyl-formamide;
for 2h;
Inert atmosphere;
DOI:10.1039/c2cc31294h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydroxide
1.2: Reflux
2.1: trifluoroacetic acid / dichloromethane; water
3.1: triethylamine; dmap / dichloromethane / Inert atmosphere
4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol / Inert atmosphere
With
dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide;
In
dichloromethane; water;
DOI:10.1021/jacs.6b07334
- Guidance literature:
-
Multi-step reaction with 3 steps
1: trifluoroacetic acid / dichloromethane; water
2: triethylamine; dmap / dichloromethane / Inert atmosphere
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol / Inert atmosphere
With
dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; water;
DOI:10.1021/jacs.6b07334
