(R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

Base Information

Chemical Name:(R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate
CAS No.:1361214-44-9
Molecular Formula:C₃₆H₃₈IN₃O₆
Molecular Weight:735.619
Hs Code.:

Synonyms:(R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

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Chemical Property of (R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

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Technology Process of (R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

There total 10 articles about (R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1361214-41-6
C₂₅H₂₉IN₂O₃

: 99333-55-8
2-(4(S)-phenyloxazolidin-2-on-3-yl)acetyl chloride

: 1361214-44-9
(R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h;
DOI:10.1016/j.bmc.2011.12.013

Reference yield:

: 512785-16-9
D-aspartic acid β-tert-butyl ester α-[(R)-α-methylbenzyl]amide

: 1361214-44-9
(R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 20 °C / desiccating agent

2: triethylamine / dichloromethane / 1 h / 0 - 20 °C

With triethylamine; In dichloromethane;
DOI:10.1016/j.bmc.2011.12.013

Reference yield:

: 745078-70-0
(E)-3-(3-iodophenyl)prop-2-en-1-ol

: 1361214-44-9
(R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate

Guidance literature:: Multi-step reaction with 3 steps

1: dipyridinium dichromate / dichloromethane / 20 °C / Inert atmosphere

2: dichloromethane / 20 °C / desiccating agent

3: triethylamine / dichloromethane / 1 h / 0 - 20 °C

With dipyridinium dichromate; triethylamine; In dichloromethane;
DOI:10.1016/j.bmc.2011.12.013