Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro-

Base Information

Chemical Name:Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro-
CAS No.:81257-91-2
Molecular Formula:C₁₂H₁₀ClNO₃
Molecular Weight:251.669
Hs Code.:
DSSTox Substance ID:DTXSID70230993
Wikidata:Q83111791
Mol file:81257-91-2.mol

Synonyms:81257-91-2;Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro-;1,7,8,9-Tetrahydro-5-chloropyrano(2,3-g)indole-2-carboxylic acid;Acide 5-chloro-7,8,9-trihydro-pyranno(2,3-g)indole-2-carboxylique [French];Acide 5-chloro-7,8,9-trihydro-pyranno(2,3-g)indole-2-carboxylique;SCHEMBL10743425;DTXSID70230993;LS-127365

Suppliers and Price of Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,7,8,9-TETRAHYDRO-5-CHLOROPYRANO(2,3-G)INDOLE-2-CARBOXYLIC ACID 95.00%
5MG
$ 499.22

Total 3 raw suppliers

Chemical Property of Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro-

Chemical Property:

Vapor Pressure:2.2E-12mmHg at 25°C
Boiling Point:537.5°C at 760 mmHg
Flash Point:278.9°C
PSA：62.32000
Density:1.532g/cm³
LogP:2.84450
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:251.0349209
Heavy Atom Count:17
Complexity:325

Purity/Quality:: 1,7,8,9-TETRAHYDRO-5-CHLOROPYRANO(2,3-G)INDOLE-2-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C3C(=CC(=C2OC1)Cl)C=C(N3)C(=O)O

Technology Process of Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro-

There total 6 articles about Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 81257-88-7
chloro-5 tetrahydro-1,7,8,9 pyranno<2,3-g>indolecarboxylate-2 de methyle

: 81257-91-2
acide chloro-5 tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

Guidance literature:: With hydrogenchloride; potassium hydroxide; water; 1) reflux, 3.5 h; 2) 0 deg C;
DOI:10.1139/v82-298

Reference yield: 93.0%

: 81257-91-2
acide chloro-5 tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

Guidance literature:

Reference yield:

: 81258-19-7
bromo-6 chloro-8 chromanne

: 81257-91-2
acide chloro-5 tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

Guidance literature:: Multi-step reaction with 4 steps

1: 1) n-butyllithium / 1) ether, -70 deg C, 6 h; 2) ether, -70 deg C, 12 h

2: Na / methanol / 6 h / 0 °C

3: 55.5 percent / N₂ / various solvent(s) / 0.33 h / 110 °C

4: 93 percent / 1) KOH, H₂O; 2) 5 N HCl / 1) reflux, 3.5 h; 2) 0 deg C

With hydrogenchloride; potassium hydroxide; n-butyllithium; nitrogen; water; sodium; In methanol;
DOI:10.1139/v82-298