Chemical Property of Piboserod
Chemical Property:
- Vapor Pressure:5.12E-13mmHg at 25°C
- Melting Point:110-113°
- Boiling Point:570.3°C at 760 mmHg
- PKA:13.86±0.20(Predicted)
- Flash Point:298.7°C
- PSA：46.50000
- Density:1.22g/cm3
- LogP:3.99450
- Storage Temp.:2-8°C
- XLogP3:3.7
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:6
- Exact Mass:369.24162724
- Heavy Atom Count:27
- Complexity:492
- Purity/Quality:
-
99%, *data from raw suppliers
SB-207266 ≥98% (HPLC) *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCCN1CCC(CC1)CNC(=O)C2=C3N(CCCO3)C4=CC=CC=C42
- Recent ClinicalTrials:Prevention Of Recurrence Of Atrial Fibrillation
- Recent EU Clinical Trials:A Proof of Biological Efficacy Study Assessing the Potential of Piboserod a Specific 5-HT4 Antagonist for the Treatment of Symptomatic Congestive Heart Failure in stable outpatients NYHA class II-III on top of Usual Evidence Based Pharmacological treatment
-
Uses
Treatment
of irritable bowel syndrome (selective 5HT4receptor
antagonist). Piboserod is a 5-HT4 receptor antagonist which has shown positive results as a Hepatitis C virus (HCV) entry inhibtor.
