(S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Base Information

Chemical Name:(S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate
CAS No.:1172614-00-4
Molecular Formula:C₂₃H₂₆N₂O₂*H₂O₄S
Molecular Weight:460.551
Hs Code.:

Synonyms:(S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Suppliers and Price of (S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of (S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

There total 7 articles about (S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 242478-37-1,180272-14-4
solifenacin

: 1172614-00-4
(S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Guidance literature:: With sulfuric acid; In di-isopropyl ether; at 20 ℃; Product distribution / selectivity;

Reference yield:

: 64-04-0
phenethylamine

: 1172614-00-4
(S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

: (R)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: sodium methylate / N,N-dimethyl-formamide; toluene; methanol / 4 h / Heating

3: acetic acid; sulfuric acid / 30 °C / Cooling with ice

4: sulfuric acid / ethyl acetate; ethanol / 0 - 50 °C

With sulfuric acid; sodium methylate; acetic acid; triethylamine; In methanol; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene;

Reference yield:

: 1416618-74-0
(R)-quinuclidin-3-yl phenethylcarbamate

: 1172614-00-4
(S)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

: (R)-((R)-quinuclidin-3-yl) 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrogensulfate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; sulfuric acid / 30 °C / Cooling with ice

2: sulfuric acid / ethyl acetate; ethanol / 0 - 50 °C

With sulfuric acid; acetic acid; In ethanol; ethyl acetate;