6-methylprednisolone 17-methoxyacetate

Base Information

• Chemical Name: 6-methylprednisolone 17-methoxyacetate
• CAS No.: 86282-02-2
• Molecular Formula: C25H34 O7
• Molecular Weight: 0
• Mol file: 86282-02-2.mol

Synonyms:6-methylprednisolone 17-methoxyacetate

Chemical Property of 6-methylprednisolone 17-methoxyacetate

Chemical Property:

• Vapor Pressure: 8.65E-18mmHg at 25°C
• Boiling Point: 616.7°C at 760 mmHg
• Flash Point: 205.9°C
• PSA: 110.13000
• Density: 1.27g/cm³
• LogP: 2.00090

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-methylprednisolone 17-methoxyacetate

There total 5 articles about 6-methylprednisolone 17-methoxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.3%

→ 11β,21-dihydroxy-17α-methoxyacetoxy-6α-methyl-1,4-pregnadiene-3,20-dione (86282-02-2) + 11β-hydroxy-17α-methoxyacetoxy-6α-methyl-21-(methylthio)acetoxy-1,4-pregnadiene-3,20-dione (89472-48-0)

Guidance literature:

Reference yield: 61.9%

→ 11β,21-dihydroxy-17α-methoxyacetoxy-6α-methyl-1,4-pregnadiene-3,20-dione (86282-02-2)

Guidance literature:

Reference yield:

11β,17α,21-trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione 17,21-ethyl orthomethoxyacetate (89472-43-5) → 11β,21-dihydroxy-17α-methoxyacetoxy-6α-methyl-1,4-pregnadiene-3,20-dione (86282-02-2)

Guidance literature:

With oxalic acid; In methanol; at 40 - 45 ℃; for 0.166667h;

DOI:10.1248/cpb.34.1607

upstream raw materials:

11β,17α,21-trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione 17,21-ethyl orthomethoxyacetate

Methylprednisolone