N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate

Base Information

Chemical Name:N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate
CAS No.:1096020-94-8
Molecular Formula:C₃₇H₃₆N₆O₁₂
Molecular Weight:756.726
Hs Code.:
Mol file:1096020-94-8.mol

Synonyms:C₃₇H₃₆N₆O₁₂

Suppliers and Price of N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(4,4''-Dimethoxytrityl)-8-nitroguanosine2'',3'',5''-Triacetate
500mg
$ 1320.00

Medical Isotopes, Inc.
N-(4,4??-Dimethoxytrityl)-8-nitroguanosine2??,3??,5??-Triacetate
500 mg
$ 2200.00

Medical Isotopes, Inc.
N-(4,4??-Dimethoxytrityl)-8-nitroguanosine2??,3??,5??-Triacetate
50 mg
$ 650.00

Total 4 raw suppliers

Chemical Property of N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate

Chemical Property:

Storage Temp.:-20°C Freezer
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

97% ^*data from raw suppliers

N-(4,4''-Dimethoxytrityl)-8-nitroguanosine2'',3'',5''-Triacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Protected 8-Nitroguanosine (N496050). Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Protected 8-Nitroguanosine (N496050). N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate is used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides.

Technology Process of N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate

There total 3 articles about N-(4,4'-DiMethoxytrityl)-8-nitroguanosine 2',3',5'-Triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1096020-93-7
C₃₇H₃₆BrN₅O₁₀

: 1096020-94-8
C₃₇H₃₆N₆O₁₂

Guidance literature:: With potassium nitrite; 18-crown-6 ether; In N,N-dimethyl-formamide; at 100 ℃; for 6h; Inert atmosphere;
DOI:10.1039/b810771h

Reference yield:

: 6979-94-8
2',3',5'-tri-O-acetyl-guanosine

: 1096020-94-8
C₃₇H₃₆N₆O₁₂

Guidance literature:: Multi-step reaction with 3 steps

1: bromine / water / 20 °C

2: pyridine / 8.08 h / 20 °C / Inert atmosphere

3: 18-crown-6 ether; potassium nitrite / N,N-dimethyl-formamide / 8 h / 100 °C / Inert atmosphere

With pyridine; potassium nitrite; 18-crown-6 ether; bromine; In water; N,N-dimethyl-formamide;
DOI:10.1080/15257770.2015.1114127

Reference yield:

: 118-00-3
G

: 1096020-94-8
C₃₇H₃₆N₆O₁₂

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; dmap / acetonitrile / 2 h / 20 °C / Cooling with ice

2: bromine / water / 20 °C

3: pyridine / 8.08 h / 20 °C / Inert atmosphere

4: 18-crown-6 ether; potassium nitrite / N,N-dimethyl-formamide / 8 h / 100 °C / Inert atmosphere

With pyridine; dmap; potassium nitrite; 18-crown-6 ether; bromine; triethylamine; In water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1080/15257770.2015.1114127