N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

Base Information

Chemical Name:N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide
CAS No.:1207079-05-7
Molecular Formula:C₂₄H₂₂F₆N₄O₂
Molecular Weight:512.455
Hs Code.:

Synonyms:N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

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Chemical Property of N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

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Technology Process of N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

There total 5 articles about N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1207088-77-4
2-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-1H-isoindole-1,3(2H)-dione

: 75-31-0
isopropylamine

: 1207079-05-7
N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

Guidance literature:: acetic acid; In 1,4-dioxane; for 3h; Reflux;

Reference yield:

: 18515-14-5
4-(chloromethyl)-2-methyl-1-nitro-benzene

: 1207079-05-7
N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 60 °C

2: iron; acetic acid / 5 h / 40 °C

3: acetic acid / 3 h / Reflux

4: acetic acid / 1,4-dioxane / 3 h / Reflux

With iron; potassium carbonate; acetic acid; acetic acid; In 1,4-dioxane; acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 866638-66-6
1-(3-methyl-4-nitrobenzyl)-3,5-bis(trifluoromethyl)-1H-pyrazole

: 1207079-05-7
N-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-N'-[(1-methylethyl)]-1,2-benzenedicarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: iron; acetic acid / 5 h / 40 °C

2: acetic acid / 3 h / Reflux

3: acetic acid / 1,4-dioxane / 3 h / Reflux

With iron; acetic acid; acetic acid; In 1,4-dioxane; acetic acid;