(S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Base Information

Chemical Name:(S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine
CAS No.:1446008-12-3
Molecular Formula:C₂₁H₂₆N₂O₂
Molecular Weight:338.45
Hs Code.:

Synonyms:(S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Suppliers and Price of (S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

There total 4 articles about (S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethyl)-carbamic acid tert-butyl ester

: 1446008-12-3
(S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;

Reference yield:

: 1446008-07-6
3-(4-cyclopropylmethoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester

: 1446008-12-3
(S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

2: sodium t-butanolate; johnphos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 12 h / 45 °C

3: trifluoroacetic acid / dichloromethane / 1 h / 0 °C

With hydrogenchloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifluoroacetic acid; johnphos; sodium t-butanolate; In 1,4-dioxane; dichloromethane;

Reference yield:

: 1446008-06-5
3-(4-cyclopropylmethoxy-phenoxy)-azetidine

: 1446008-12-3
(S)-1-{4-[3-(4-cyclopropylmethoxy-phenoxy)-azetidin-1-yl]-phenyl}-ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium t-butanolate; johnphos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 12 h / 45 °C

2: trifluoroacetic acid / dichloromethane / 1 h / 0 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifluoroacetic acid; johnphos; sodium t-butanolate; In 1,4-dioxane; dichloromethane;