3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

Base Information

Chemical Name:3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine
CAS No.:1023717-35-2
Molecular Formula:C₁₄H₁₂BrN₃O₂S
Molecular Weight:366.238
Hs Code.:

Synonyms:3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

Chemical Property:

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Technology Process of 3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

There total 2 articles about 3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1023717-37-4
6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

: 1023717-35-2
3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

Reference yield:

: 14793-00-1
6-chloro-2-methylimidazo-<1,2-b>pyridazine

: 1023717-35-2
3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / water; N,N-dimethyl-formamide / 5 h / 105 °C

2: N-Bromosuccinimide / N,N-dimethyl-formamide / 3 h / 0 - 20 °C

With N-Bromosuccinimide; potassium carbonate; bis-triphenylphosphine-palladium(II) chloride; In water; N,N-dimethyl-formamide;

Reference yield:

: 402718-29-0
3-cyanopyridine-5-boronic acid pinacol ester

: 1023717-35-2
3-bromo-6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

: 1083428-87-8
5-[6-(4-methanesulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-nicotinonitrile

Guidance literature:: With potassium carbonate; bis-triphenylphosphine-palladium(II) chloride; In water; N,N-dimethyl-formamide; at 105 ℃; for 4.5h;