10-O-deacetyl larotaxel

Base Information

Chemical Name:10-O-deacetyl larotaxel
CAS No.:158811-30-4
Molecular Formula:C₄₃H₅₁NO₁₃
Molecular Weight:789.877
Hs Code.:

Synonyms:10-O-deacetyl larotaxel

Suppliers and Price of 10-O-deacetyl larotaxel

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-O-deacetyl larotaxel

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 10-O-deacetyl larotaxel

There total 17 articles about 10-O-deacetyl larotaxel which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2′-O-(tert-butyldimethylsilyl)-10-O-deacetyllarotaxel

: 158811-30-4
10-O-deacetyl larotaxel

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 40 ℃; for 3h; pH=7;
DOI:10.1016/j.ejmech.2018.07.029

Reference yield:

: 95603-44-4
7,10-di-(2,2,2-trichloroethyloxycarbonyl)-10-deacetylbaccatin III

: 158811-30-4
10-O-deacetyl larotaxel

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) DCC, DMAP, 2.) Zn powder, AcOH / 1.) toluene, 20 deg C, 1.5 h, 2.) AcOEt, 20 deg C, 16 h

2: 91 percent / pyridine / CH₂Cl₂ / -35 - 0 °C

3: 95 percent / NaN₃ / tetrahydrofuran; acetonitrile / 1 h / Heating

4: HCOOH / 1 h / 20 °C

5: CH₂Cl₂ / 64 h / 20 °C

With pyridine; dmap; formic acid; sodium azide; acetic acid; dicyclohexyl-carbodiimide; zinc; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1016/0040-4039(94)88367-X

Reference yield:

: 143615-03-6,143527-70-2
(4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid

: 158811-30-4
10-O-deacetyl larotaxel

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) DCC, DMAP, 2.) Zn powder, AcOH / 1.) toluene, 20 deg C, 1.5 h, 2.) AcOEt, 20 deg C, 16 h

2: 91 percent / pyridine / CH₂Cl₂ / -35 - 0 °C

3: 95 percent / NaN₃ / tetrahydrofuran; acetonitrile / 1 h / Heating

4: HCOOH / 1 h / 20 °C

5: CH₂Cl₂ / 64 h / 20 °C

With pyridine; dmap; formic acid; sodium azide; acetic acid; dicyclohexyl-carbodiimide; zinc; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1016/0040-4039(94)88367-X