-D-phenylalanine O-

Base Information

Chemical Name:-D-phenylalanine O-
CAS No.:159579-70-1
Molecular Formula:C₄₂H₄₇N₃O₁₂
Molecular Weight:785.848
Hs Code.:

<N-(tert-Butoxycarbonyl)-(R)-3-hydroxy-4-methoxyphenylglycinyl>-D-phenylalanine O-<N-(benzyloxycarbonyl)-(S)-2-methyl-3-methoxyphenylglycine methyl ester>

Synonyms:-D-phenylalanine O-

Suppliers and Price of -D-phenylalanine O-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of -D-phenylalanine O-

Chemical Property:

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Technology Process of -D-phenylalanine O-

There total 1 articles about -D-phenylalanine O- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 159579-69-8
-D-phenylalanine (methoxyethoxy)methyl ester O-

: 159579-70-1
-D-phenylalanine O-

Guidance literature:: With magnesium bromide; In diethyl ether; for 26h; Ambient temperature;
DOI:10.1021/jo00088a010

Reference yield:

: 159579-70-1
-D-phenylalanine O-

: (R)-2-((R)-2-{3-[5-((S)-Amino-methoxycarbonyl-methyl)-3-methoxy-2-methyl-phenoxy]-4-methoxy-phenyl}-2-tert-butoxycarbonylamino-acetylamino)-3-phenyl-propionic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 1h;
DOI:10.1021/jo00088a010

Reference yield:

: 159579-70-1
-D-phenylalanine O-

: (8S,11R,14R)-11-Benzyl-14-tert-butoxycarbonylamino-5,18-dimethoxy-4-methyl-10,13-dioxo-2-oxa-9,12-diaza-tricyclo[13.3.1.1^3,7]icosa-1⁽¹⁸⁾,3⁽²⁰⁾,4,6,15⁽¹⁹⁾,16-hexaene-8-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd-C / ethanol / 1 h

2: EDC, HOBT / CH₂Cl₂ / 1.) 0 deg C, 4 h, 2.) room temp., 12 h

With hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jo00088a010