7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Base Information

• Chemical Name: 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• CAS No.: 147059-75-4
• Molecular Formula: C20H15F3N4O3
• Molecular Weight: 0
• Mol file: 147059-75-4.mol

Synonyms:7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Chemical Property of 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Chemical Property:

• Vapor Pressure: 2.59E-24mmHg at 25°C
• Melting Point: >250°C (dec.)
• Boiling Point: 630.5°Cat760mmHg
• Flash Point: 335.1°C
• PSA: 164.20000
• Density: g/cm³
• LogP: 3.24460
• Storage Temp.: Desiccate at RT
• Solubility.: DMSO: >10mg/mL

Purity/Quality:

98%,99%, ^*data from raw suppliers

Trovafloxacin mesylate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 63-34
• Safety Statements: 26-36-45

MSDS Files:

SDS file from LookChem

Useful:

• Description: Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC50 = 3.02 μg/ml) and DNA gyrase (IC50 = 7.13 μg/ml).
• Uses: Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.
• Therapeutic Function: Antibacterial