N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide

Base Information

Chemical Name:N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide
CAS No.:22839-13-0
Molecular Formula:C₁₉H₂₀N₄O₃
Molecular Weight:352.393
Hs Code.:
DSSTox Substance ID:DTXSID101226977

Synonyms:SCHEMBL5189427;DTXSID101226977;N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide;22839-13-0

Suppliers and Price of N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:352.15354051
Heavy Atom Count:26
Complexity:481

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NN
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NN

Technology Process of N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide

There total 5 articles about N-[(Phenylmethoxy)carbonyl]-L-tryptophan hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 2717-76-2,130812-44-1,130812-46-3
(S)-N-benzyloxycarbonyl-L-tryptophan methyl ester

: 22839-13-0
benzyl (S)-(1-hydrazinyl-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate

Guidance literature:: With hydrazine hydrate; In methanol; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1039/d0cc02728f

Reference yield:

: methyl-(benzyloxycarbonyl)-L-tryptophan

: 22839-13-0
benzyl (S)-(1-hydrazinyl-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / Inert atmosphere

2: hydrazine hydrate / methanol / 12 h / 20 °C / Inert atmosphere

With thionyl chloride; hydrazine hydrate; In methanol;
DOI:10.1039/d0cc02728f

Reference yield:

: 4299-70-1
L-tryptophan methyl ester

: 22839-13-0
benzyl (S)-(1-hydrazinyl-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / 20 °C

2: hydrazine hydrate / methanol / Reflux

With sodium hydrogencarbonate; hydrazine hydrate; In methanol;
DOI:10.1002/chem.201101423