N₁-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N₂-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide

Base Information

• Chemical Name: N₁-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N₂-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide
• CAS No.: 866635-99-6
• Molecular Formula: C₂₅H₂₃F₇N₄O₂S
• Molecular Weight: 576.538

Synonyms:N₁-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N₂-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide

Chemical Property of N₁-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N₂-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide

Chemical Property:

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Technology Process of N₁-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N₂-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide

There total 1 articles about N₁-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N₂-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-methyl-2-methylsulfanylethylamine (741658-04-8) + 2-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-4-fluoro-1H-isoindole-1,3(2H)-dione (866638-68-8) → N1-{4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-ylmethyl]-2-methylphenyl}-3-fluoro-N2-[1-(S)-1-methyl-2-methylsulfanyl-ethyl]-phthalamide (866635-99-6)

Guidance literature:

With acetic acid; In 1,4-dioxane; for 18h; Heating / reflux;

upstream raw materials:

(S)-1-methyl-2-methylsulfanylethylamine

2-(4-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylphenyl)-4-fluoro-1H-isoindole-1,3(2H)-dione

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