diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Base Information

Chemical Name:diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate
CAS No.:94138-57-5
Molecular Formula:C₄₃H₄₈O₅Si
Molecular Weight:672.937
Hs Code.:

Synonyms:diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Suppliers and Price of diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

There total 10 articles about diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.6%

: 94138-51-9
diphenylmethyl (R)-5-hydroxy-2(E)-hexenoate

: 94138-52-0
(R)-7-(tert-butyldiphenylsiloxy)-4-octynoic acid

: 94138-57-5
diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In diethyl ether; for 48h; Ambient temperature;
DOI:10.1021/jo00204a009

Reference yield:

: 62992-46-5
1-(tetrahydropyranyloxy)-4-pentyn

: 94138-57-5
diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) n-BuLi, 2.) HMPA / 1.) THF, 0 deg C, 1 h, 2.) RT, 10 h

2: 18.46 g / imidazole / dimethylformamide / 12 h / 35 °C

3: 13.16 g / pyridinium p-toluenesulfonate / ethanol / 20 h / Ambient temperature

4: 82.1 percent / Jones reagent / acetone / 0.25 h / 0 °C

5: 82.6 percent / DCC,DMAP / diethyl ether / 48 h / Ambient temperature

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; n-butyllithium; jones reagent; pyridinium p-toluenesulfonate; dicyclohexyl-carbodiimide; In diethyl ether; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jo00204a009

Reference yield:

: 91603-57-5
(2E,5R)-5-hydroxy-2-hexenoic acid

: 94138-57-5
diphenylmethyl (2E,5R,13R)-13-(tert-butyldiphenylsiloxy)-5-methyl-6-oxa 7-oxotetradec-2-en-10-ynoate

Guidance literature:: Multi-step reaction with 2 steps

1: 80.1 percent / ethyl acetate / 24 h / Ambient temperature

2: 82.6 percent / DCC,DMAP / diethyl ether / 48 h / Ambient temperature

With dmap; dicyclohexyl-carbodiimide; In diethyl ether; ethyl acetate;
DOI:10.1021/jo00204a009