ethyl (E)-3-[bis(2-chloroethyl)amino]-3-phenylprop-2-enoate

Base Information

Chemical Name:ethyl (E)-3-[bis(2-chloroethyl)amino]-3-phenylprop-2-enoate
CAS No.:18352-56-2
Molecular Formula:C₁₅H₁₉Cl₂NO₂
Molecular Weight:316.227
Hs Code.:
NSC Number:72148
DSSTox Substance ID:DTXSID70421268
Wikidata:Q82232692
Mol file:18352-56-2.mol

Synonyms:NSC72148;18352-56-2;DTXSID70421268;NSC-72148

Suppliers and Price of ethyl (E)-3-[bis(2-chloroethyl)amino]-3-phenylprop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of ethyl (E)-3-[bis(2-chloroethyl)amino]-3-phenylprop-2-enoate

Chemical Property:

Vapor Pressure:1.13E-07mmHg at 25°C
Boiling Point:432.1°Cat760mmHg
Flash Point:215.2°C
Density:1.187g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:315.0792842
Heavy Atom Count:20
Complexity:309

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=C(C1=CC=CC=C1)N(CCCl)CCCl
Isomeric SMILES:CCOC(=O)/C=C(\C1=CC=CC=C1)/N(CCCl)CCCl

Technology Process of ethyl (E)-3-[bis(2-chloroethyl)amino]-3-phenylprop-2-enoate

There total 3 articles about ethyl (E)-3-[bis(2-chloroethyl)amino]-3-phenylprop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18352-53-9
(Z)-3-[Bis-(2-methanesulfonyloxy-ethyl)-amino]-3-phenyl-acrylic acid ethyl ester

: 18352-56-2
(Z)-3-[Bis-(2-chloro-ethyl)-amino]-3-phenyl-acrylic acid ethyl ester

Guidance literature:: With lithium chloride; In N,N-dimethyl-formamide;
DOI:10.1021/jm00316a040

Reference yield:

: 18352-50-6
(Z)-3-[Bis-(2-hydroxy-ethyl)-amino]-3-phenyl-acrylic acid ethyl ester

: 18352-56-2
(Z)-3-[Bis-(2-chloro-ethyl)-amino]-3-phenyl-acrylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Py / CHCl₃

2: LiCl / dimethylformamide

With pyridine; lithium chloride; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm00316a040

Reference yield:

: 2216-94-6
phenylpropynoic acid ethyl ester

: 18352-56-2
(Z)-3-[Bis-(2-chloro-ethyl)-amino]-3-phenyl-acrylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: Py / CHCl₃

3: LiCl / dimethylformamide

With pyridine; lithium chloride; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm00316a040