Technology Process of (1RS,2RS,4SR,5SR,6RS,7s,8SR)-6,8-bis(benzyloxy)-7-methyl-3,9-dioxatricyclo[3.3.1.0(2,4)]nonane
There total 6 articles about (1RS,2RS,4SR,5SR,6RS,7s,8SR)-6,8-bis(benzyloxy)-7-methyl-3,9-dioxatricyclo[3.3.1.0(2,4)]nonane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 20 ℃;
stereoselective reaction;
DOI:10.1016/j.tet.2012.05.029
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / -60 °C
2: sodium hydride / tetrahydrofuran / 0 - 20 °C
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C
With
lithium aluminium tetrahydride; sodium hydride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane;
2: Williamson reaction;
DOI:10.1016/j.tet.2012.05.029
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sulfuric acid / 1 h / 50 - 55 °C
2: potassium carbonate / acetone / 36 h / 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / -60 °C
4: sodium hydride / tetrahydrofuran / 0 - 20 °C
5: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C
With
lithium aluminium tetrahydride; sulfuric acid; sodium hydride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; acetone;
4: Williamson reaction;
DOI:10.1016/j.tet.2012.05.029
![(1RS,2RS,3r,4SR,5SR)-2,4-bis(benzyloxy)-3-methyl-8-oxabicyclo[3.2.1]oct-6-ene](/Databaselist/images/loading.webp)
