5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

Base Information

• Chemical Name: 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal
• CAS No.: 359642-16-3
• Molecular Formula: C₂₂H₃₃BrO₅S₂
• Molecular Weight: 521.537

Synonyms:5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

Chemical Property of 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

There total 3 articles about 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

acetic anhydride (108-24-7) + 4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal (359642-15-2) → 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal (359642-16-3)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/S0008-6215(01)00116-1

Reference yield:

4-O-benzyl-2,3:5,6-di-O-isopropylidene-D-glucose diethyl dithioacetal (149557-49-3) → 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal (359642-16-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / AcOH / H₂O / 20 °C

2: 61 percent / PPh₃; CBr₄ / tetrahydrofuran / 0.75 h / 20 °C

3: 51 percent / pyridine / 20 °C

With pyridine; carbon tetrabromide; acetic acid; triphenylphosphine; In tetrahydrofuran; water;

DOI:10.1016/S0008-6215(01)00116-1

Reference yield:

4-O-benzyl-2,3-O-isopropylidene-D-glucose diethyl dithioacetal (359642-14-1) → 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal (359642-16-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / PPh₃; CBr₄ / tetrahydrofuran / 0.75 h / 20 °C

2: 51 percent / pyridine / 20 °C

With pyridine; carbon tetrabromide; triphenylphosphine; In tetrahydrofuran;

DOI:10.1016/S0008-6215(01)00116-1

upstream raw materials:

acetic anhydride

4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

4-O-benzyl-2,3:5,6-di-O-isopropylidene-D-glucose diethyl dithioacetal

4-O-benzyl-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

Downstream raw materials:

1L(1,2,4/3,5)-1-O-acetyl-2-O-benzyl-5-benzyloxyamino-3,4-O-isopropylidenecyclohexan-1,2,3,4-tetrol

5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose O-benzyloxime

1L(1,2,4/3,5)-1-O-acetyl-2-O-benzyl-3,4-O-isopropylidene-5-C-methoxycarbonylmethylcyclohexan-1,2,3,4-tetrol

methyl 7-O-acetyl-4-O-benzyl-8-bromo-2,3,8-trideoxy-4,5-O-isopropylidene-D-gluco-oct-2-enonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 359642-16-3 5-O-acetyl-4-O-benzyl-6-bromo-6-deoxy-2,3-O-isopropylidene-D-glucose diethyl dithioacetal

Send

Send

Metric Ton KG G Pound L ML

Send

Send