4-(4-chlorophenoxy)-2-trifluoromethylquinazoline

Base Information

• Chemical Name: 4-(4-chlorophenoxy)-2-trifluoromethylquinazoline
• CAS No.: 337924-79-5
• Molecular Formula: C₁₅H₈ClF₃N₂O
• Molecular Weight: 324.69
• Mol file: 337924-79-5.mol

Synonyms:4-(4-chlorophenoxy)-2-trifluoromethylquinazoline

Chemical Property of 4-(4-chlorophenoxy)-2-trifluoromethylquinazoline

Chemical Property:

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Technology Process of 4-(4-chlorophenoxy)-2-trifluoromethylquinazoline

There total 1 articles about 4-(4-chlorophenoxy)-2-trifluoromethylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-chloro-phenol (106-48-9,82344-39-6) + 4-chloro-2-trifluoromethyl quinazoline (52353-35-2) → 4-(4-chlorophenoxy)-2-trifluoromethylquinazoline (337924-79-5)

Guidance literature:

4-chloro-phenol; With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 0.333333h; Inert atmosphere;

4-chloro-2-trifluoromethyl quinazoline; In dimethyl sulfoxide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.ejmech.2011.06.021

upstream raw materials:

4-chloro-phenol

4-chloro-2-trifluoromethyl quinazoline