11-phenoxyundecyl-malonic acid

Base Information

• Chemical Name: 11-phenoxyundecyl-malonic acid
• CAS No.: 1225274-26-9
• Molecular Formula: C₂₀H₃₀O₅
• Molecular Weight: 350.455
• Mol file: 1225274-26-9.mol

Synonyms:11-phenoxyundecyl-malonic acid

Chemical Property of 11-phenoxyundecyl-malonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 11-phenoxyundecyl-malonic acid

There total 1 articles about 11-phenoxyundecyl-malonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cycl-isopropylidene malonate (2033-24-1) + 11-phenoxy-1-undecanol (19097-15-5) → 11-phenoxyundecyl-malonic acid (1225274-26-9)

Guidance literature:

In toluene; for 1h; Reflux;

DOI:10.1016/j.carres.2009.12.022

Reference yield: 63.0%

11-phenoxyundecyl-malonic acid (1225274-26-9) + 3,4,6-tri-O-benzyl-2-acetamido-2-deoxyamino-α-D-glucopyranose (121123-45-3) → 3,4,6-tri-O-benzyl-2-acetamido-2-deoxy-β-D-glucopyranosyl 11-phenoxyundecyl malonate (1225274-40-7) + 3,4,6-tri-O-benzyl-2-acetamido-2-deoxy-α-D-glucopyranosyl 11-phenoxyundecyl malonate (1225274-27-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 1.5h; optical yield given as %de;

DOI:10.1016/j.carres.2009.12.022

upstream raw materials:

cycl-isopropylidene malonate

11-phenoxy-1-undecanol

Downstream raw materials:

3,4,6-tri-O-benzyl-2-acetamido-2-deoxy-β-D-glucopyranosyl 11-phenoxyundecyl malonate

3,4,6-tri-O-benzyl-2-acetamido-2-deoxy-α-D-glucopyranosyl 11-phenoxyundecyl malonate