N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide

Base Information

• Chemical Name: N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide
• CAS No.: 315203-56-6
• Molecular Formula: C₁₉H₂₅NO₆
• Molecular Weight: 363.411
• Mol file: 315203-56-6.mol

Synonyms:N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide

Chemical Property of N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide

There total 3 articles about N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-benzyl hydroxylalmine (622-30-0) + (3aS,3bR,7aS,8aR)-2,2,5,5-tetramethyltetrahydro-8aH-[1,3]dioxolo[4′,5′:4,5]furo[3,2-d][1,3]dioxine-8a-carbaldehyde (55385-72-3) → N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide (315203-56-6)

Guidance literature:

In diethyl ether; at 0 ℃; for 1h;

DOI:10.1039/b003959o

Reference yield:

dikegulac (18467-77-1) → N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide (315203-56-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / K₂CO₃ / various solvent(s) / 4 h / Heating

2: 58 percent / DIBAL / hexane / 5.5 h / -78 °C

3: 98 percent / diethyl ether / 1 h / 0 °C

With diisobutylaluminium hydride; potassium carbonate; In diethyl ether; hexane; 1: Methylation / 2: Reduction / 3: Condensation;

DOI:10.1039/b003959o

Reference yield:

methyl 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonate (52507-90-1) → N-(1-deoxo-2,3:4,6-di-O-isoprpylidene-α-L-xylo-hex-2-ul-1-ylidene)benzylamine N-oxide (315203-56-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / DIBAL / hexane / 5.5 h / -78 °C

2: 98 percent / diethyl ether / 1 h / 0 °C

With diisobutylaluminium hydride; In diethyl ether; hexane; 1: Reduction / 2: Condensation;

DOI:10.1039/b003959o

upstream raw materials:

N-benzyl hydroxylalmine

(3aS,3bR,7aS,8aR)-2,2,5,5-tetramethyltetrahydro-8aH-[1,3]dioxolo[4′,5′:4,5]furo[3,2-d][1,3]dioxine-8a-carbaldehyde

dikegulac

methyl 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonate