1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea

Base Information

Chemical Name:1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea
CAS No.:869090-02-8
Molecular Formula:C₃₆H₄₅N₃O₅
Molecular Weight:599.77
Hs Code.:

Synonyms:1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea

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Chemical Property of 1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea

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Technology Process of 1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea

There total 2 articles about 1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 869090-01-7
4(S)-benzyl-3-[2(S)-ethoxy-3-(3'-(methylamino)biphenyl-4-yl)propionyl]oxazolidin-2-one trifluoroacetate

: 4747-81-3
N-heptylisocyanate

: 869090-02-8
1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 20h;

Reference yield:

: tert-butyl (S)-{4'-[3-(4-benzyl-2-oxooxazolidin-3-yl)-2-ethoxy-3-oxopropyl]biphenyl-3-yl}-methylcarbamate

: 869090-02-8
1-{4'-[3-(4(S)-benzyl-2-oxooxazolidin-3-yl)-2(S)-ethoxy-3-oxopropyl]biphenyl-3-yl}-3-heptyl-1-methylurea

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 24 h / 20 °C

2: triethylamine / dichloromethane / 20 h / 20 °C

With triethylamine; trifluoroacetic acid; In dichloromethane;