di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Base Information

Chemical Name:di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate
CAS No.:293329-47-2
Molecular Formula:C₂₄H₄₅O₃PS
Molecular Weight:444.659
Hs Code.:

Synonyms:di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Suppliers and Price of di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

There total 4 articles about di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 293329-46-1
di-(l)-menthyl (allylsulfanyl)methylphosphonate

: ((R)-1-Mercapto-but-3-enyl)-phosphonic acid bis-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester

: 293329-47-2
di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In tetrahydrofuran; at -70 ℃; for 1.16667h; Title compound not separated from byproducts;
DOI:10.1080/10426509908546454

Reference yield:

: 211183-18-5
hydrogen di[(1R,2S,5R)-menthyl] phosphite

: 293329-47-2
di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium hydride / tetrahydrofuran / 3 h / 0 °C

1.2: tetrahydrofuran / 2 h / 20 °C

1.3: 82 percent / tetrahydrofuran / 20 °C

2.1: NaBH₄ / ethanol / 5 h / 0 - 70 °C

3.1: 95 percent / 20 °C

4.1: sec-BuLi; HMPA / tetrahydrofuran; cyclohexane / 1.25 h / -75 - -72 °C

4.2: HCl / H₂O

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium tetrahydroborate; sec.-butyllithium; potassium hydride; In tetrahydrofuran; ethanol; cyclohexane; 1.1: Deprotonation / 1.2: Addition / 1.3: Methylation / 2.1: Reduction / 3.1: Addition / 4.1: Rearrangement / 4.2: Hydrolysis;
DOI:10.1021/ol005937j

Reference yield:

: Mercaptomethyl-phosphonic acid bis-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester

: 293329-47-2
di-(l)menthyl (1-mercaptobut-3-enyl)phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 95 percent / 20 °C

2.1: sec-BuLi; HMPA / tetrahydrofuran; cyclohexane / 1.25 h / -75 - -72 °C

2.2: HCl / H₂O

With N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium; In tetrahydrofuran; cyclohexane; 1.1: Addition / 2.1: Rearrangement / 2.2: Hydrolysis;
DOI:10.1021/ol005937j