(1S,2S)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2-diol

Base Information

Chemical Name:(1S,2S)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2-diol
CAS No.:132065-10-2
Molecular Formula:C₁₀H₁₃N₅O₂
Molecular Weight:235.246
Hs Code.:

Synonyms:1,2-Cyclopentanediol,4-(6-amino-9H-purin-9-yl)-, (1a,2b,4a)- (9CI); 1,2-Cyclopentanediol, 4-(6-amino-9H-purin-9-yl)-,(1a,2b,4a)-(?à)-

Suppliers and Price of (1S,2S)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of (1S,2S)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2-diol

Chemical Property:

Vapor Pressure:2.74E-12mmHg at 25°C
Boiling Point:535.3°Cat760mmHg
Flash Point:277.5°C
Density:1.89g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1S,2S)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2-diol

There total 7 articles about (1S,2S)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 132065-15-7
(+/-)-(1α,2β,4α)-4-(6-chloro-9H-purin-9-yl)-1,2-cyclopentanediol

: 132065-10-2
(+/-)-(1α,2β,4β)-4-(6-amino-9H-purin-9-yl)-1,2-cyclopentanediol

Guidance literature:: With ammonia; In methanol; at 100 ℃; for 48h;
DOI:10.1016/S0040-4039(00)97979-6 DOI:10.1021/jm00090a007

Reference yield:

: (+/-)-(1α,2β,4β)-4-amino-1,2-cyclopentanediol

: 132065-10-2
(+/-)-(1α,2β,4β)-4-(6-amino-9H-purin-9-yl)-1,2-cyclopentanediol

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / butan-1-ol / 24 h / Heating

2: 1.) conc. HCl, 2.) conc. HCl, MeOH / 1.) reflux, 12 h, 2.) RT, 30 min

3: 80 percent / NH₃ / methanol / 48 h / 100 °C

With hydrogenchloride; methanol; ammonia; triethylamine; In methanol; butan-1-ol;
DOI:10.1021/jm00090a007

Reference yield:

: 132065-12-4
4-benzamidocyclopentene

: 132065-10-2
(+/-)-(1α,2β,4β)-4-(6-amino-9H-purin-9-yl)-1,2-cyclopentanediol

Guidance literature:: Multi-step reaction with 7 steps

1: 96 percent / MCPBA / CHCl₃ / 1 h / Ambient temperature

2: 2percent aq.H₂SO₄ / 1 h / Ambient temperature

3: pyridine / Ambient temperature

4: 6N HCl / H₂O / 24 h / Heating

5: Et₃N / butan-1-ol / 24 h / Heating

6: 1.) conc. HCl, 2.) conc. HCl, MeOH / 1.) reflux, 12 h, 2.) RT, 30 min

7: 80 percent / NH₃ / methanol / 48 h / 100 °C

With pyridine; hydrogenchloride; methanol; sulfuric acid; ammonia; triethylamine; 3-chloro-benzenecarboperoxoic acid; In methanol; chloroform; water; butan-1-ol;
DOI:10.1021/jm00090a007