tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

Base Information

Chemical Name:tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate
CAS No.:1434873-87-6
Molecular Formula:C₂₆H₃₉N₇O₇S
Molecular Weight:593.704
Hs Code.:

Synonyms:tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

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Chemical Property of tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

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Technology Process of tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

There total 10 articles about tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1434875-15-6
C₁₂H₁₉N₅O₃S

: (S)-2-(1-((tert-butoxycarbonyl)amino)-3-methylbutyl)oxazole-4-carboxylic acid

: 1434873-87-6
tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

Reference yield:

: C₁₅H₂₈N₂O₆

: 1434873-87-6
tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

Guidance literature:: Multi-step reaction with 4 steps

1: diethylamino-sulfur trifluoride / dichloromethane / -78 °C

2: Bromotrichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane

3: water; sodium hydroxide / methanol

4: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide

With Bromotrichloromethane; diethylamino-sulfur trifluoride; water; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 1434873-87-6
tert-butyl ((S)-1-(4-(((S)-5-guanidino-1-oxo-1-(phenylsulfonamido)pentan-2-yl)carbamoyl)oxazol-2-yl)-3-methylbutyl)carbamate

Guidance literature:: Multi-step reaction with 5 steps

1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide

2: diethylamino-sulfur trifluoride / dichloromethane / -78 °C

3: Bromotrichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane

4: water; sodium hydroxide / methanol

5: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide

With Bromotrichloromethane; diethylamino-sulfur trifluoride; water; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;