4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide

Base Information

• Chemical Name: 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide
• CAS No.: 1160498-02-1
• Molecular Formula: C₁₀H₁₂N₆O₃S
• Molecular Weight: 296.31
• Mol file: 1160498-02-1.mol

Synonyms:4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide

Chemical Property of 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide

There total 2 articles about 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ethyl 5-amino-1-(4-sulfamoylphenyl)-1H-pyrazole-4-carboxylate (72292-62-7) → 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide (1160498-02-1)

Guidance literature:

With hydrazine hydrate; In ethanol; for 8h; Reflux;

DOI:10.1002/ardp.200800178

Reference yield:

4-hydrazinobenzene-1-sulfonamide hydrochloride → 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide (1160498-02-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / ethanol / 3 h / Reflux

2: hydrazine hydrate / 8 h / Reflux

With hydrazine hydrate; sodium acetate; In ethanol;

DOI:10.1007/s00706-015-1549-x

Reference yield: 92.0%

5-nitrooxindole (20870-79-5) + 4-[5-amino-4-(hydrazinocarbonyl)-1H-pyrazol-1-yl]benzenesulfonamide (1160498-02-1) → 4-(5-amino-4-(2-(5-nitro-2-oxoindolin-3-ylidene)hydrazine-1-carbonyl)-1H-pyrazol-1-yl)benzenesulfonamide

Guidance literature:

With acetic acid; In ethanol; for 1h; Reflux;

DOI:10.1016/j.ejmech.2015.09.021

upstream raw materials:

ethyl 5-amino-1-(4-sulfamoylphenyl)-1H-pyrazole-4-carboxylate

Downstream raw materials:

C₁₁H₁₀N₆O₃S₂

C₁₇H₁₅ClN₆O₃S

C₁₇H₁₆N₆O₃S

4-{[4-(2-benzoylhydrazinocarbonyl)]-5-amino-1H-pyrazol-1-yl}benzenesulfonamide