1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone

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Chemical Name:1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone
CAS No.:1207283-02-0
Molecular Formula:C₂₈H₃₆F₂N₈O₇
Molecular Weight:634.64
Hs Code.:

Synonyms:1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone

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Chemical Property of 1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone

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Technology Process of 1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone

There total 1 articles about 1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 226569-29-5
[N,N'-di-(tert-butoxycarbonyl)]-2-ethoxyguanidine

: 1207283-01-9
[6-cyano-3-(2,2-difluoro-2-phenyl-ethylamino)-2-oxo-2H-pyrazin-1-yl]-acetic acid

: 1207283-02-0
1-{N-[2-(N',N''-bis{tert-butoxycarbonyl}aminidino-aminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone

Guidance literature:: With benzotriazole-1-yl-oxy-tris-(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1021/jm901802n