N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

Base Information

• Chemical Name: N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate
• CAS No.: 475174-67-5
• Molecular Formula: C₉H₁₁N₂*C₉H₁₁O₃S
• Molecular Weight: 346.45
• Mol file: 475174-67-5.mol

Synonyms:N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

Chemical Property of N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

There total 3 articles about N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(but-1-yn-1-yl)pyridine (475174-64-2) + mesitylenesulfonylhydroxylamine (36016-40-7) → N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (475174-67-5)

Guidance literature:

In dichloromethane; at 0 ℃; for 0.5h;

Reference yield:

1-(but-1-yn-1-yl)pyridine (475174-64-2) + N-hydroxy-2,4,6-trimethylbenzensulfonamide (58042-39-0) → N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (475174-67-5)

Guidance literature:

In dichloromethane; at 0 ℃; for 0.5h;

Reference yield:

2-bromo-pyridine (109-04-6) → N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (475174-67-5)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / diethylamine / 10 h / 20 °C

2: dichloromethane / 1 h / 0 °C / Cooling with ice

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In dichloromethane; diethylamine;

DOI:10.1021/jm300259r

upstream raw materials:

1-(but-1-yn-1-yl)pyridine

mesitylenesulfonylhydroxylamine

N-hydroxy-2,4,6-trimethylbenzensulfonamide

2-bromo-pyridine

Downstream raw materials:

[7-(2-chloro-4-methoxyphenyl)-2-ethylpyrazolo[1,5-a]pyridin-3-yl]amine

7-(2-chloro-4-methoxyphenyl)-N,N-bis(cyclopropylmethyl)-2-ethylpyrazolo[1,5-a]pyridin-3-amine

N-cyclopropylmethyl-N-[2-ethyl-7-(2-methoxy-4,6-dimethylphenyl)pyrazolo[1,5-a]pyridin-3-yl]amine

N,N-bis(cyclopropylmethyl)-2-ethyl-7-(4-methoxy-2-methylphenyl)pyrazolo[1,5-a]pyridin-3-amine