Technology Process of dimethyl-thiocarbamic acid S-(4-bromo-3,5-dimethyl-phenyl) ester
There total 1 articles about dimethyl-thiocarbamic acid S-(4-bromo-3,5-dimethyl-phenyl) ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triethylamine / dmap / 1,4-dioxane / 20 h / Heating / reflux
2: tetradecane / Heating / reflux
With
triethylamine;
dmap;
In
1,4-dioxane; tetradecane;
- Guidance literature:
-
dimethyl-thiocarbamic acid S-(4-bromo-3,5-dimethyl-phenyl) ester;
With
sodium methylate;
In
methanol;
for 20h;
Inert atmosphere;
Reflux;
With
hydrogenchloride;
In
methanol; water;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium methylate / methanol / 20 h / Heating / reflux
2.1: tributylphosphine; 1,1'-azodicarbonyl-dipiperidine / toluene / 0 - 20 °C
3.1: sodium hydroxide; water / tetrahydrofuran
4.1: 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine / dichloromethane / 20 °C
4.2: 20 °C
5.1: potassium fluoride / tetrakis(triphenylphosphine) palladium(0) / toluene / Heating / reflux
6.1: sodium hydroxide; water / tetrahydrofuran
With
4-methyl-morpholine; potassium fluoride; sodium hydroxide; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; tributylphosphine; water; sodium methylate; 1,1'-azodicarbonyl-dipiperidine;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; methanol; dichloromethane; toluene;
2.1: Mitsunobu reaction / 5.1: Suzuki Coupling;
