Technology Process of Fmoc-Ala-NH-Dpm(C22)
There total 7 articles about Fmoc-Ala-NH-Dpm(C22) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
chloroform;
at 20 ℃;
for 3h;
DOI:10.1021/ol302002g
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium tetrahydroborate / tetrahydrofuran; methanol / 60 °C
2: methanesulfonic acid / toluene / 100 °C
3: sodium hydroxide / Alkaline conditions
4: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 3 h / 20 °C
With
sodium tetrahydroborate; methanesulfonic acid; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
tetrahydrofuran; methanol; chloroform; toluene;
DOI:10.1021/ol302002g
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 80 °C
2: sodium tetrahydroborate / tetrahydrofuran; methanol / 60 °C
3: methanesulfonic acid / toluene / 100 °C
4: sodium hydroxide / Alkaline conditions
5: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 3 h / 20 °C
With
sodium tetrahydroborate; methanesulfonic acid; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
tetrahydrofuran; methanol; chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol302002g
