(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Base Information

Chemical Name:(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine
CAS No.:125049-26-5
Molecular Formula:C₂₆H₂₆N₂O₂
Molecular Weight:398.505
Hs Code.:

(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzo<a,d>cyclohepten-5,10-imine

Synonyms:(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Suppliers and Price of (5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

There total 4 articles about (5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₁H₃₄N₂O₄

: 125049-26-5
(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

: 125134-21-6
(5S,10R)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.5h; Yield given. Yields of byproduct given;
DOI:10.1021/jm00164a052

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 125049-26-5
(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Guidance literature:: Multi-step reaction with 2 steps

2: trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 0 °C

With trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00164a052

Reference yield:

: 42982-04-7
2-methoxy-5H-dibenzo[a,d]cyclohepten-5-one

: 125049-26-5
(5R,10S)-L-phenylalanyl-8-methoxy-10,11-dihydro-5-methyl-5H-dibenzocyclohepten-5,10-imine

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / tetrahydrofuran; diethyl ether / 6 h / Ambient temperature

2: 65 percent / NH₂OH*HCl, NaOAc, Cl₂CHCO₂H / CH₂Cl₂ / 1 h / Heating

4: trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 0 °C

With dichloro-acetic acid; hydroxylamine hydrochloride; sodium acetate; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jm00164a052