5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

Base Information

Chemical Name:5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine
CAS No.:677025-67-1
Molecular Formula:C₁₉H₂₉N₆O₇P
Molecular Weight:484.449
Hs Code.:

Synonyms:5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

Suppliers and Price of 5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

Chemical Property:

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Technology Process of 5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

There total 1 articles about 5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 3095-95-2
diethylphosphonoacetic acid

: 21950-36-7
5'-amino-5'-deoxy-2',3'-O-isopropylideneadenosine

: 677025-67-1
5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

Guidance literature:: With benzotriazol-1-ol; diisopropyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.01.042

Reference yield:

: 1293967-14-2
C₂₀H₂₂O₆

: 677025-67-1
5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine

: C₃₅H₄₁N₆O₁₂P

Guidance literature:: 5’-deoxy-5’-N-[(diethylphosphono)acetyl]-2’,3’-O-isopropylideneadenosine; With 2,6-dimethylpyridine; trimethylsilyl bromide; In acetonitrile; at 20 ℃; Inert atmosphere;

With triethylamine carbonate; In water; acetonitrile; Inert atmosphere; preparative HPLC purification;

C₂₀H₂₂O₆; With pyridine; diisopropyl-carbodiimide; at 65 ℃; for 48h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.01.042