(S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate

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Chemical Name:(S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate
CAS No.:1449768-10-8
Molecular Formula:C₂₅H₃₇N₃O₃
Molecular Weight:427.587
Hs Code.:

Synonyms:(S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate

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Chemical Property of (S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate

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Technology Process of (S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate

There total 2 articles about (S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 500024-95-3
tert-butyl (Z)-2-(N'-hydroxycarbamimidoyl)pyrrolidine-1-carboxylate

: 3575-31-3
4-octylbenzoic acid

: 1449768-10-8
(S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 - 100 ℃; for 3h;

Reference yield: 19.0%

: 3575-31-3
4-octylbenzoic acid

: C₁₀H₁₈N₂O₄

: 1449768-10-8
(S)-tert-butyl 2-(5-(4-octylphenyl)-1,2,4-oxadiazol-3-yl)-pyrrolidine-1-carboxylate

Guidance literature:: With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 - 80 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jm501760d