C₁₂H₁₃ClO

Base Information

• Chemical Name: C₁₂H₁₃ClO
• CAS No.: 1413394-04-3
• Molecular Formula: C₁₂H₁₃ClO
• Molecular Weight: 208.688
• Mol file: 1413394-04-3.mol

Synonyms:C₁₂H₁₃ClO

Chemical Property of C₁₂H₁₃ClO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₃ClO

There total 3 articles about C₁₂H₁₃ClO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

1-[2-(2-methylprop-1-en-1-yl)phenyl]ethanone (38552-83-9) → C12H13ClO (1413394-04-3) + 2,2-dichloro-1-[2-(2-methylprop-1-en-1-yl)phenyl]ethanone (1413394-06-5)

Guidance literature:

1-[2-(2-methylprop-1-en-1-yl)phenyl]ethanone; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 2h;

With chloro-trimethyl-silane; In tetrahydrofuran; at 0 ℃; for 6h;

With N-chloro-succinimide; In tetrahydrofuran; for 8h;

DOI:10.1002/hlca.201200396 DOI:10.1002/hlca.201200396

Reference yield:

1-formyl-2-(2,2-dimethylethenyl)benzene (91388-35-1) → C12H13ClO (1413394-04-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 0 °C

2.1: pyridinium chlorochromate / dichloromethane / 20 °C

3.1: lithium diisopropyl amide / tetrahydrofuran / 2 h / -78 °C

3.2: 6 h / 0 °C

3.3: 8 h

With pyridinium chlorochromate; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1002/hlca.201200396 DOI:10.1002/hlca.201200396

Reference yield:

C12H16O → C12H13ClO (1413394-04-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridinium chlorochromate / dichloromethane / 20 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 2 h / -78 °C

2.2: 6 h / 0 °C

2.3: 8 h

With pyridinium chlorochromate; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1002/hlca.201200396 DOI:10.1002/hlca.201200396

upstream raw materials:

1-[2-(2-methylprop-1-en-1-yl)phenyl]ethanone

1-formyl-2-(2,2-dimethylethenyl)benzene