5-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine

Base Information

Chemical Name:5-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine
CAS No.:923732-22-3
Molecular Formula:C₁₁H₈ClF₃N₂S
Molecular Weight:292.712
Hs Code.:
European Community (EC) Number:870-032-5

Synonyms:5-{[4-chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine;923732-22-3;5-[[4-chloro-3-(trifluoromethyl)phenyl]methyl]-1,3-thiazol-2-amine;5-[4-chloro-3-(trifluoromethyl)benzyl]-1,3-thiazol-2-amine;AKOS000134871;CS-0243520;EN300-26478;Z223460098

Suppliers and Price of 5-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:292.0048816
Heavy Atom Count:18
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1CC2=CN=C(S2)N)C(F)(F)F)Cl

Technology Process of 5-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine

There total 1 articles about 5-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-1,3-thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1185908-19-3
C₁₀H₇Cl₂F₃O

: 17356-08-0
thiourea

: 923732-22-3
C₁₁H₈ClF₃N₂S

Guidance literature:: In ethanol; for 2h; Reflux; Inert atmosphere;
DOI:10.1002/ardp.200800201

Reference yield: 71.0%

: 923732-22-3
C₁₁H₈ClF₃N₂S

3,4-dihydro-2H-1-benzopyran-3-carboxylic acid: 115822-57-6
3,4-dihydro-2H-1-benzopyran-3-carboxylic acid

: 924824-24-8
N-{5-[4-chloro-3-(trifluoromethyl)benzyl]-1,3-thiazol-2-yl}chromane-3-carboxamide

Guidance literature:: 3,4-dihydro-2H-1-benzopyran-3-carboxylic acid; With 1,1'-carbonylbis(3-methyl-1H-imidazol-3-ium) triflate; In 1,4-dioxane; nitromethane; at 40 ℃; for 0.333333h; Inert atmosphere;

C₁₁H₈ClF₃N₂S; In 1,4-dioxane; nitromethane; at 70 ℃; for 2h; Microwave irradiation; Inert atmosphere;
DOI:10.1002/ardp.200800201