Altemicidin

Base Information

Chemical Name:Altemicidin
CAS No.:125399-82-8
Molecular Formula:C13H20 N4 O7 S
Molecular Weight:376.39
Hs Code.:
UNII:39E2X82JVD
DSSTox Substance ID:DTXSID20925120
Nikkaji Number:J717.021A
Wikipedia:Altemicidin
Wikidata:Q76416503
Metabolomics Workbench ID:106219
ChEMBL ID:CHEMBL3586273
Mol file:125399-82-8.mol

Synonyms:altemicidin

Suppliers and Price of Altemicidin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ALTEMICIDIN 95.00%
5MG
$ 497.44

Total 14 raw suppliers

Chemical Property of Altemicidin

Chemical Property:

PSA：194.98000
Density:1.547g/cm³
LogP:0.48610
XLogP3:-2.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:376.10527016
Heavy Atom Count:25
Complexity:744

Purity/Quality:

99% ^*data from raw suppliers

ALTEMICIDIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC2C(CC(C2(C(=O)O)NC(=O)CS(=O)(=O)N)O)C(=C1)C(=O)N
Isomeric SMILES:CN1C[C@@H]2[C@@H](C[C@@H]([C@]2(C(=O)O)NC(=O)CS(=O)(=O)N)O)C(=C1)C(=O)N

Technology Process of Altemicidin

There total 16 articles about Altemicidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 170711-36-1
(4aR,6S,7R,7aS)-6-Hydroxy-2-methyl-7-(2-sulfamoyl-acetylamino)-4-(2,2,2-trifluoro-acetyl)-2,4a,5,6,7,7a-hexahydro-1H-[2]pyrindine-7-carboxylic acid

: 125399-82-8
(-)-Altemicidin

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; sodium amide; In benzene; at 80 ℃; for 0.666667h;
DOI:10.1021/ja00147a032

Reference yield:

: 170711-29-2
C₁₉H₂₆N₂O₄

: 125399-82-8
(-)-Altemicidin

Guidance literature:: Multi-step reaction with 12 steps

1: 87 percent / H₂ / 10percent Pd/C / H₂O

2: 100 percent / H₂O₂ / methanol

3: 65 percent / pyridine / CH₂Cl₂

4: 92 percent / DMAP / acetonitrile

5: 94 percent / aq.LiOH / tetrahydrofuran

6: Dess-Martin periodinane / CH₂Cl₂

7: NaClO₂ / 2-methyl-propan-2-ol

8: 85 percent / tetrahydrofuran

9: 70 percent / catecholborane bromide / CH₂Cl₂ / 0.25 h / Ambient temperature

10: 87 percent / 1,1'-carbonyldiimidazole / tetrahydrofuran

11: 88 percent / LiSPr-n, HMPA / 2 h / Ambient temperature

12: 50 percent / NaNH₂, DABCO / benzene / 0.67 h / 80 °C

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium hydroxide; sodium chlorite; bromocatecholborane; hydrogen; dihydrogen peroxide; lithium n-propylmercaptide; Dess-Martin periodane; sodium amide; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; acetonitrile; tert-butyl alcohol; benzene;
DOI:10.1021/ja00147a032

Reference yield:

: 170711-21-4
C₁₉H₂₄N₂O₅

: 125399-82-8
(-)-Altemicidin

Guidance literature:: Multi-step reaction with 13 steps

1: 85 percent / LiAl(OEt)2H₂ / diethyl ether

2: 87 percent / H₂ / 10percent Pd/C / H₂O

3: 100 percent / H₂O₂ / methanol

4: 65 percent / pyridine / CH₂Cl₂

5: 92 percent / DMAP / acetonitrile

6: 94 percent / aq.LiOH / tetrahydrofuran

7: Dess-Martin periodinane / CH₂Cl₂

8: NaClO₂ / 2-methyl-propan-2-ol

9: 85 percent / tetrahydrofuran

10: 70 percent / catecholborane bromide / CH₂Cl₂ / 0.25 h / Ambient temperature

11: 87 percent / 1,1'-carbonyldiimidazole / tetrahydrofuran

12: 88 percent / LiSPr-n, HMPA / 2 h / Ambient temperature

13: 50 percent / NaNH₂, DABCO / benzene / 0.67 h / 80 °C

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium hydroxide; sodium chlorite; bromocatecholborane; hydrogen; dihydrogen peroxide; lithium n-propylmercaptide; Dess-Martin periodane; sodium amide; lithium diethoxyaluminum hydride; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; acetonitrile; tert-butyl alcohol; benzene;
DOI:10.1021/ja00147a032