11-cis,13-cis-12-carboxyretinol

Base Information

• Chemical Name: 11-cis,13-cis-12-carboxyretinol
• CAS No.: 83803-36-5
• Molecular Formula: C₂₁H₃₀O₃
• Molecular Weight: 330.467
• Mol file: 83803-36-5.mol

Synonyms:11-cis,13-cis-12-carboxyretinol

Chemical Property of 11-cis,13-cis-12-carboxyretinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-cis,13-cis-12-carboxyretinol

There total 2 articles about 11-cis,13-cis-12-carboxyretinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

methyl 11-cis,13-cis-12-carboxyretinoate (83860-28-0) → 11-cis,13-cis-12-(Hydroxymethyl)retinol (88315-66-6) + 11-cis,13-cis-12-carboxyretinol (83803-36-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

DOI:10.1021/jo00178a014

Reference yield: 29.0%

methyl 11-cis,13-cis-12-carboxyretinoate (83860-28-0) → 11-cis,13-cis-12-carboxyretinol (83803-36-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h;

DOI:10.1021/jo00150a016

Reference yield:

11-cis,13-cis-12-carboxyretinol (83803-36-5) → 11-cis,13-cis-12-Carboxyretinol δ-Lactone (83860-25-7)

Guidance literature:

In cyclohexane; for 6h; Yield given; Heating;

DOI:10.1021/jo00150a016

upstream raw materials:

methyl 11-cis,13-cis-12-carboxyretinoate

Downstream raw materials:

11-cis,13-cis-12-Carboxyretinol δ-Lactone