N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

Base Information

Chemical Name:N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine
CAS No.:910906-47-7
Molecular Formula:C₁₇H₂₃N₅O₂S
Molecular Weight:361.468
Hs Code.:

Synonyms:N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

Suppliers and Price of N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

There total 2 articles about N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 910906-52-4
C₁₇H₂₁N₅O₄S

: 910906-47-7
N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; ethyl acetate; for 2h;

Reference yield:

: 867333-33-3
1-[3-(4-bromo-benzenesulfonyl)-propyl]-pyrrolidine

: 910906-47-7
N-[4-(3-pyrrolidin-1-yl-propane-1-sulfonyl)-phenyl]-pyrimidine-2,5-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 5 h / 100 °C

2: hydrogen / palladium 10% on activated carbon / methanol; ethyl acetate / 2 h

With hydrogen; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium 10% on activated carbon; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; methanol; ethyl acetate;