benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

Base Information

Chemical Name:benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate
CAS No.:700866-67-7
Molecular Formula:C₂₆H₂₈F₂N₂O₄
Molecular Weight:470.516
Hs Code.:

Synonyms:benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

Chemical Property:

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Technology Process of benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

There total 1 articles about benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 700866-66-6
[3-tert-butoxycarbonylamino-4-(3,5-difluoro-phenyl)-2-hydroxy-butyl]-(3-methoxybenzyl)-carbamic acid benzyl ester

: 700866-67-7
benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

Guidance literature:: With trifluoroacetic acid; at 0 - 20 ℃; for 1h;

Reference yield:

: 700866-67-7
benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

: 700866-69-9
{4-(3,5-difluoro-phenyl)-3-[3-(2-dipropylcarbamoyl-ethyl)-ureido]-2-hydroxy-butyl}-(3-methoxybenzyl)-carbamic acid benzyl ester

Guidance literature:: 3-(N,N-dipropylcarbamoyl)propionic acid; With diphenyl phosphoryl azide; triethylamine; In toluene; at 20 - 90 ℃; for 1.25h;

benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate; In toluene; at 0 - 20 ℃; for 1h;

Reference yield:

: 700866-67-7
benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate

: 700866-70-2
{4-(3,5-difluoro-phenyl)-3-[3-(2-dipropylsulfamoyl-ethyl)-ureido]-2-hydroxy-butyl}-(3-methoxybenzyl)-carbamic acid benzyl ester

Guidance literature:: 3-dipropylsulfamoyl-propionic acid; With diphenyl phosphoryl azide; triethylamine; In toluene; at 20 - 90 ℃; for 1.25h;

benzyl (2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl(3-methoxybenzyl)carbamate; In toluene; at 0 - 20 ℃; for 1h;