17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Base Information

Chemical Name:17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan
CAS No.:1373214-73-3
Molecular Formula:C₂₇H₂₉IN₂O₄
Molecular Weight:572.443
Hs Code.:

Synonyms:17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Suppliers and Price of 17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

There total 3 articles about 17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 91487-18-2
2,5-dioxopyrrolidin-1-yl 3-iodobenzoate

: β-3-methoxynaloxamine

: 1373214-73-3
17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm300305c

Reference yield:

: 131830-09-6,70866-64-7
Naloxone methyl ether

: 1373214-73-3
17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonium acetate / methanol / 0.17 h / 20 °C / Inert atmosphere

1.2: 24 h / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere

With ammonium acetate; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;
DOI:10.1021/jm300305c

Reference yield:

: 618-51-9
3-Iodobenzoic acid

: 1373214-73-3
17-allyl-4,5α-epoxy-14β-hydroxy-3-methoxy-6β-[(3-iodo)benzamido]morphinan

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere

With N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm300305c