1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol

Base Information

• Chemical Name: 1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol
• CAS No.: 448960-37-0
• Molecular Formula: C₁₉H₂₂O₃S
• Molecular Weight: 330.448
• Mol file: 448960-37-0.mol

Synonyms:1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol

Chemical Property of 1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol

There total 1 articles about 1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

cyclopropylphenylsulfide (14633-54-6) + p-acetonyloxyanisole (6698-71-1) → 1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol (448960-37-0)

Guidance literature:

cyclopropylphenylsulfide; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 5h;

p-acetonyloxyanisole; In tetrahydrofuran; hexane; at 20 ℃; for 16h; Further stages.;

DOI:10.1021/ol026199x

Reference yield: 77.0%

1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol (448960-37-0) → 7-methoxy-2a-methyl-8b-(phenylsulfanyl)1,2a,3,8b-tetrahydro-2H-cyclobuta[c]chromene

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 4h; Heating;

DOI:10.1021/ol026199x

Reference yield:

1-(4-methoxyphenoxy)-2-[1-(phenylsulfanyl)cyclopropyl]-2-propanol (448960-37-0) → 6-methoxy-3-methyl-4-(2-phenylsulfanyl-ethyl)-2H-chromene

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / p-toluenesulfonic acid monohydrate / benzene / 4 h / Heating

2: benzene / 20 h / Heating

With toluene-4-sulfonic acid; In benzene;

DOI:10.1021/ol026199x

upstream raw materials:

cyclopropylphenylsulfide

p-acetonyloxyanisole

Downstream raw materials:

2-[(4-methoxyphenyl)methyl]-2-methylcyclobutanone