Technology Process of 2-(4-hexyl-5-(4-(diphenylamino)phen-1-yl)thiophen-2-yl)-6-(4-hexyl-5-bromothiophen-2-yl)benzo[1,2-d;4,5-d']bisthiazole
There total 4 articles about 2-(4-hexyl-5-(4-(diphenylamino)phen-1-yl)thiophen-2-yl)-6-(4-hexyl-5-bromothiophen-2-yl)benzo[1,2-d;4,5-d']bisthiazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); caesium carbonate;
In
water; N,N-dimethyl-formamide;
at 120 ℃;
for 16h;
Schlenk technique;
Inert atmosphere;
DOI:10.1002/ejoc.201201629
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-Bromosuccinimide / chloroform; acetic acid / 4 h / 20 °C / Schlenk technique; Inert atmosphere; Darkness
2: tetrakis(triphenylphosphine) palladium(0); caesium carbonate / water; N,N-dimethyl-formamide / 16 h / 120 °C / Schlenk technique; Inert atmosphere
With
N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium(0); caesium carbonate;
In
chloroform; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201201629
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 2,2,6,6-tetramethyl-piperidine; tert.-butyl lithium / tetrahydrofuran; pentane / -78 °C / Schlenk technique; Inert atmosphere
1.2: -78 - 20 °C / Schlenk technique; Inert atmosphere
2.1: N,N-dimethyl-formamide / 16 h / 120 °C / Schlenk technique; Inert atmosphere
3.1: N-Bromosuccinimide / chloroform; acetic acid / 4 h / 20 °C / Schlenk technique; Inert atmosphere; Darkness
4.1: tetrakis(triphenylphosphine) palladium(0); caesium carbonate / water; N,N-dimethyl-formamide / 16 h / 120 °C / Schlenk technique; Inert atmosphere
With
2,2,6,6-tetramethyl-piperidine; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium(0); tert.-butyl lithium; caesium carbonate;
In
tetrahydrofuran; chloroform; water; acetic acid; N,N-dimethyl-formamide; pentane;
DOI:10.1002/ejoc.201201629