(S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

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Chemical Name:(S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate
CAS No.:1246168-67-1
Molecular Formula:C₂₂H₂₄N₄O₅
Molecular Weight:424.456
Hs Code.:

Synonyms:(S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

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Chemical Property of (S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

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Technology Process of (S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

There total 3 articles about (S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1246168-78-4
Z-Phe-ψ-[CONHNHCSNH]-L-Ala-OMe

: 1246168-67-1
(S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

Guidance literature:: With pyridine; p-toluenesulfonyl chloride; In tetrahydrofuran; for 3h; Reflux;
DOI:10.1016/j.tetlet.2010.07.004

Reference yield:

: C₂₂H₂₆N₄O₅Se

: 1246168-67-1
(S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

Guidance literature:: With iodine; triethylamine; In tetrahydrofuran; at 0 ℃; for 0.25h; Green chemistry;
DOI:10.1039/c7nj02278f

Reference yield:

: 21887-86-5
N-benzyloxycarbonyl-L-phenylalanine hydrazide

: 1258863-42-1
C₅H₇NO₂Se

: 1246168-67-1
(S)-methyl-2-((5-((S)-1-(((benzyloxy)carbonyl)amino)-2-phenylethyl)-1,3,4-oxadiazol-2-yl)amino)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 20 °C

2: triethylamine; iodine / tetrahydrofuran / 0.25 h / 0 °C / Green chemistry

With iodine; triethylamine; In tetrahydrofuran;
DOI:10.1039/c7nj02278f