N₁-(4-chloro-3-fluorophenyl)-N₂-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide

Base Information

• Chemical Name: N₁-(4-chloro-3-fluorophenyl)-N₂-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide
• CAS No.: 1226787-88-7
• Molecular Formula: C₂₀H₂₅ClFN₃O₂
• Molecular Weight: 393.889

Synonyms:N₁-(4-chloro-3-fluorophenyl)-N₂-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide

Chemical Property of N₁-(4-chloro-3-fluorophenyl)-N₂-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide

Chemical Property:

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Technology Process of N₁-(4-chloro-3-fluorophenyl)-N₂-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide

There total 1 articles about N₁-(4-chloro-3-fluorophenyl)-N₂-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

ethyl 2-((4-chloro-3-fluorophenyl)amino)-2-oxoacetate (1226789-23-6) + 2-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)isoindoline-1,3-dione (1226789-25-8) → N1-(4-chloro-3-fluorophenyl)-N2-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)oxalamide (1226787-88-7)

Guidance literature:

2-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)isoindoline-1,3-dione; With methylhydrazine; In ethanol; for 5h; Reflux;

ethyl 2-((4-chloro-3-fluorophenyl)amino)-2-oxoacetate; In ethanol; at 150 ℃; Microwave; Inert atmosphere;

upstream raw materials:

ethyl 2-((4-chloro-3-fluorophenyl)amino)-2-oxoacetate

2-(2,2,6,6-tetramethyl-1-(prop-2-ynyl)piperidin-4-yl)isoindoline-1,3-dione

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