C₁₉H₂₀O₃

Base Information

• Chemical Name: C₁₉H₂₀O₃
• CAS No.: 1610378-61-4
• Molecular Formula: C₁₉H₂₀O₃
• Molecular Weight: 296.366
• Mol file: 1610378-61-4.mol

Synonyms:C₁₉H₂₀O₃

Chemical Property of C₁₉H₂₀O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₉H₂₀O₃

There total 1 articles about C₁₉H₂₀O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E/Z)-2-buten-1-ol (6117-91-5,542-72-3) + 1,3-diphenylpropanedione (120-46-7,61346-73-4) → C19H20O3 (1610378-61-4) + C19H20O3

Guidance literature:

With (S)-2-{bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilanyl)oxy]methyl}pyrrolidine; triscarbonyl‐(η⁴–3,4‐bis(4‐methoxyphenyl)‐2,5‐diphenylcyclopenta‐2,4‐dienone)iron; trimethylamine-N-oxide; In 5,5-dimethyl-1,3-cyclohexadiene; at 20 ℃; for 66h; Reagent/catalyst; Solvent; Temperature; Overall yield = 96 %; Overall yield = 57.1 mg; enantioselective reaction; Catalytic behavior;

DOI:10.1021/ol500821c

Reference yield:

C19H20O3 (1610378-61-4) → (3R,5R)-5-hydroxy-3-methyl-5-phenylpentyl benzoate + (3R,5S)-5-hydroxy-3-methyl-5-phenylpentyl benzoate

Guidance literature:

C₁₉H₂₀O₃; With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 2.75h;

With hydrogenchloride; In diethyl ether; water; at 20 ℃; for 0.5h; Overall yield = 87 %; Overall yield = 79.2 mg; Optical yield = 13.043 %de;

DOI:10.1021/ol500821c

Reference yield:

C19H20O3 (1610378-61-4) → (2R,2R)-4-methyl-2-phenyl-tetrahydro-2H-pyran (149713-23-5,149713-24-6) + (2S,2R)-4-methyl-2-phenyl-tetrahydro-2H-pyran (149713-23-5,149713-24-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 2.75 h / 20 °C

1.2: 0.5 h / 20 °C

2.1: trifluorormethanesulfonic acid / dichloromethane / 1 h / 0 °C / Inert atmosphere

2.2: Inert atmosphere

With lithium aluminium tetrahydride; trifluorormethanesulfonic acid; In diethyl ether; dichloromethane;

DOI:10.1021/ol500821c

upstream raw materials:

(E/Z)-2-buten-1-ol

1,3-diphenylpropanedione

Downstream raw materials:

(2R,2R)-4-methyl-2-phenyl-tetrahydro-2H-pyran

(2S,2R)-4-methyl-2-phenyl-tetrahydro-2H-pyran