(1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone

Base Information

• Chemical Name: (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone
• CAS No.: 628293-71-0
• Molecular Formula: C₁₉H₂₁NO
• Molecular Weight: 279.382
• Mol file: 628293-71-0.mol

Synonyms:(1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone

Chemical Property of (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone

There total 2 articles about (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzylcyclohexa-2,5-dienyl-1-carboxylic acid (52457-04-2) → (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone (628293-71-0)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride; pyridine / CH₂Cl₂ / 0.5 h / 20 °C

2: 180 mg / pyridine / CH₂Cl₂

With pyridine; oxalyl dichloride; In dichloromethane;

DOI:10.1021/ja030407e

Reference yield:

1,2,3,6-tetrahydropyridine (694-05-3) + 1-benzyl-1,4-dihydrobenzoic acid chloride → (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone (628293-71-0)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1021/ja030407e

Reference yield: 85.0%

iron pentacarbonyl (13463-40-6,71564-23-3,37220-42-1) + (1-benzylcyclohexa-2,5-dienyl)(3,6-dihydro-2H-pyridin-1-yl)methanone (628293-71-0) → [Fe(CO)3(C6H5(CH2C6H5)CONCHCH2CH2CH2CH2)]

Guidance literature:

With carbon monoxide; In dibutyl ether; reflux under CO atmosphere for 24 - 36 h;

DOI:10.1021/ja030407e

upstream raw materials:

1,2,3,6-tetrahydropyridine

1-benzylcyclohexa-2,5-dienyl-1-carboxylic acid